Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551596 | 0.81 | KCNH2 (0.60) | KCNH2SLC2A1 | |
| SCHEMBL3552603 | 0.81 | KCNH2 (0.60) | KCNH2SLC2A1 | |
| SCHEMBL3550302 | 0.81 | KCNH2 (0.60) | KCNH2SLC2A1 | |
| SCHEMBL3326906 | 0.78 | SLC2A1 (0.47) | KCNH2SLC2A1 | |
| SCHEMBL3224839 | 0.78 | SLC2A1 (0.47) | KCNH2SLC2A1 | |
| SCHEMBL3146445 | 0.78 | SLC2A1 (0.47) | KCNH2SLC2A1 | |
| SCHEMBL2821795 | 0.77 | KCNH2 (0.46) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3149069 | 0.77 | SLC2A1 (0.46) | KCNH2SLC2A1 | |
| SCHEMBL3546002 | 0.77 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL2930163 | 0.77 | KCNH2 (0.58) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963324-B1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS ANTIBACTERIALS | GLAXO GROUP LTD (GB) | 2010-04-21 | — | — | EP | disclosed |