SCHEMBL276820

SCHEMBL276820

CS(=O)(=O)OC1CCCC1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
HRH3 Q9Y5N1 1/20 0.34
USP2 O75604 2/20 0.33
TSHR P16473 2/20 0.33
ACHE P22303 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MMP9 P14780 1/20 0.32
ALOX15 P16050 1/20 0.32
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8366305 0.97 CA1 (0.58) CA1CA2HRH3USP2TSHR
SCHEMBL18828734 0.97 CA1 (0.58) CA1CA2HRH3USP2TSHR
SCHEMBL8370841 0.97 CA1 (0.58) CA1CA2HRH3USP2TSHR
SCHEMBL2583782 0.97 CA1 (0.58) CA1CA2HRH3USP2TSHR
SCHEMBL14779905 0.97 CA1 (0.58) CA1CA2HRH3USP2TSHR
SCHEMBL17088827 0.97 CA1 (0.58) CA1CA2HRH3USP2TSHR
SCHEMBL275547 0.97 CA1 (0.58) CA1CA2HRH3USP2TSHR
SCHEMBL28839918 0.95 CA1 (0.56) CA1CA2HRH3USP2TSHR
SCHEMBL3815211 0.94
SCHEMBL10727963 0.91 CA1 (0.52) CA1CA2HRH3ACHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11199525-A None JP disclosed
EP-4568948-A1 COMPOUNDS FOR TREATING CANCER Genesis Therapeutics, Inc. (US) 2025-06-18 EP disclosed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
WO-2024059010-A1 COMPOUNDS FOR TREATING CANCER GENESIS THERAPEUTICS, INC. (US) 2024-03-21 WO disclosed
WO-2023168686-A1 SUBSTITUTED CYCLOPENTANES AS CDK2 INHIBITORS QILU REGOR THERAPEUTICS INC. (CN) 2023-09-14 WO disclosed
US-11753397-B2 Cereblon binders for the degradation of ikaros C4 THERAPEUTICS, INC. (US) 2023-09-12 US disclosed
US-11753397-B2 Cereblon binders for the degradation of ikaros C4 THERAPEUTICS, INC. (US) 2023-09-12 US disclosed
US-11753397-B2 Cereblon binders for the degradation of ikaros C4 THERAPEUTICS, INC. (US) 2023-09-12 US disclosed
WO-2022121844-A1 DIHYDROPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 上海维申医药有限公司 2022-06-16 WO disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
US-4588743-A CARDIOVASCULAR AGENTS E. R. SQUIBB & SONS, INC. (US) 1986-05-13 US disclosed
US-4582854-A BRONCHODILATOR, ANTIINFLAMMATORY AGENT, ANALGESIC E. R. SQUIBB & SONS, INC. (US) 1986-04-15 US disclosed
US-4575512-A THROMBOXANE SYNTHETASE INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1986-03-11 US disclosed
EP-0163562-A1 7-Oxabicycloheptane substituted ethers E.R. Squibb & Sons, Inc. (US) 1985-12-04 EP disclosed
EP-0161904-A2 Tetrahydrofuranyl and tetrahydrothienyl substituted ethers E.R. Squibb & Sons, Inc. (US) 1985-11-21 EP disclosed
US-4550120-A BRONCHODILATOR AGENTS, ANALGESICS E. R. SQUIBB & SONS, INC. (US) 1985-10-29 US disclosed
US-4542151-A CARDIOVASCULAR, BRONCHODILATION, ANALGESICS, ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1985-09-17 US disclosed
US-4521539-A ANALGESICS, CARDIONVASCULAR AND ANTIINFLAMMATORY AGENTS E. R. SQUIBB & SONS, INC. (US) 1985-06-04 US disclosed
US-4454274-A Aminoplast curable coating compositions containing cycloaliphatic sulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1984-06-12 US disclosed
US-4237138-A REGULATORS OF CARDIOVASCULAR SYSTEM PFIZER INC. (US) 1980-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11753397-B2 Cereblon binders for the degradation of ikaros CRBN, IKZF1, IKZF3 CA1 3051/4885CA2 3567/4885HRH3 4527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.