Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27682179 | 0.91 | PDE10A (0.37) | PDE10AMAPTTSHRNPSR1RECQL | |
| SCHEMBL27682253 | 0.88 | PDE10A (0.36) | PDE10AMAPTTSHRNPSR1RECQL | |
| SCHEMBL27682175 | 0.88 | PDE10A (0.38) | PDE10AMAPTTSHRNPSR1RECQL | |
| SCHEMBL27662806 | 0.87 | PDE10A (0.35) | PDE10AMAPTTSHRNPSR1RECQL | |
| SCHEMBL27662579 | 0.86 | PDE10A (0.39) | PDE10AMAPTTSHRNPSR1RECQL | |
| SCHEMBL4772589 | 0.85 | MAPT (0.33) | PDE10AMAPTTSHRNPSR1RECQL | |
| SCHEMBL4776059 | 0.84 | PDE10A (0.33) | PDE10AMAPTTSHRNPSR1RECQL | |
| SCHEMBL5907441 | 0.83 | MAPT (0.36) | MAPTTSHRNPSR1RECQLSIGMAR1 | |
| SCHEMBL4772348 | 0.83 | PDE10A (0.32) | PDE10AMAPTTSHRNPSR1RECQL | |
| SCHEMBL4772353 | 0.83 | PDE10A (0.32) | PDE10AMAPTTSHRNPSR1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980927-A | Pyrazolopyridine derivatives | ASTELLAS PHARMA INC (JP) | 2007-06-13 | — | — | CN | claimed |
| CN-1980927-A | Pyrazolopyridine derivatives | ASTELLAS PHARMA INC (JP) | 2007-06-13 | — | — | CN | disclosed |