Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779625 | 0.78 | PTGIR (0.35) | PTGIRSMN1; SMN2ATMPRNPLMNA | |
| SCHEMBL4779637 | 0.78 | PTGIR (0.35) | PTGIRSMN1; SMN2ATMPRNPLMNA | |
| SCHEMBL27682177 | 0.76 | SMN1; SMN2 (0.34) | PTGIRSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL4774651 | 0.68 | PTGIR (0.46) | PTGIRPRNP | |
| SCHEMBL4774647 | 0.68 | PTGIR (0.46) | PTGIRPRNP | |
| SCHEMBL28764860 | 0.64 | PTGIR (0.41) | PTGIR | |
| SCHEMBL4774000 | 0.63 | POLB (0.37) | SMN1; SMN2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL4772738 | 0.63 | POLB (0.37) | SMN1; SMN2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL4772731 | 0.63 | POLB (0.37) | SMN1; SMN2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL4778680 | 0.63 | PTGIR (0.42) | PTGIRNPC1RAB9APRNPL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980927-A | Pyrazolopyridine derivatives | ASTELLAS PHARMA INC (JP) | 2007-06-13 | — | — | CN | disclosed |