Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 3/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27666529 | 0.91 | C5AR1 (0.38) | C5AR1TLR8TLR7BCHEACHE | |
| SCHEMBL61239 | 0.88 | NR1H4 (0.38) | C5AR1BCHEACHEMAPTCFTR | |
| SCHEMBL27666483 | 0.88 | CFTR (0.36) | C5AR1TLR8TLR7BCHEACHE | |
| SCHEMBL61114 | 0.87 | C5AR1 (0.38) | C5AR1BCHEACHESMN1; SMN2PDGFRB | |
| SCHEMBL62689 | 0.87 | C5AR1 (0.39) | C5AR1BCHEACHESMN1; SMN2ALDH1A1 | |
| SCHEMBL63231 | 0.86 | C5AR1 (0.39) | C5AR1TLR8TLR7BCHEACHE | |
| SCHEMBL27685475 | 0.86 | BCHE (0.37) | C5AR1BCHEACHESMN1; SMN2KIT | |
| SCHEMBL61189 | 0.86 | C5AR1 (0.40) | C5AR1TLR8TLR7BCHEACHE | |
| SCHEMBL62185 | 0.86 | C5AR1 (0.40) | C5AR1BCHEACHESMN1; SMN2ALDH1A1 | |
| SCHEMBL62744 | 0.85 | BCHE (0.41) | C5AR1BCHEACHESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1976918-A | 4,5-disubstituted-2-aryl pyrimidines | NEUROGEN CORP (US) | 2007-06-06 | — | — | CN | claimed |