SCHEMBL27686121

SCHEMBL27686121

BrCc1ccc2cc3cc4cc5ccccc5cc4cc3cc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.52
CYP1A2 P05177 1/20 0.52
ALDH1A1 P00352 2/20 0.46
TRPA1 O75762 1/20 0.46
TSHR P16473 1/20 0.46
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
HBB P68871 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
HTR2B P41595 1/20 0.44
PYCR1 P32322 1/20 0.42
SIGMAR1 Q99720 1/20 0.41
MC4R P32245 1/20 0.41
MC5R P33032 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5681757 1.00 CYP2A6 (0.52) CYP2A6CYP1A2ALDH1A1TRPA1TSHR
SCHEMBL29349685 0.93 CYP2A6 (0.60) CYP2A6CYP1A2ALDH1A1TRPA1TSHR
SCHEMBL29707927 0.93 CYP2A6 (0.60) CYP2A6CYP1A2ALDH1A1TRPA1TSHR
SCHEMBL44621 0.93 CYP2A6 (0.60) CYP2A6CYP1A2ALDH1A1TRPA1TSHR
SCHEMBL5349984 0.93 CYP1A2 (0.41) CYP2A6CYP1A2ALDH1A1TRPA1TSHR
SCHEMBL6259103 0.91 CYP2A6 (0.58) CYP2A6CYP1A2ALDH1A1TRPA1TSHR
SCHEMBL21644744 0.91 CYP2A6 (0.58) CYP2A6CYP1A2ALDH1A1TRPA1TSHR
SCHEMBL11028429 0.91 CYP2A6 (0.58) CYP2A6CYP1A2ALDH1A1TRPA1TSHR
SCHEMBL1721014 0.87 CYP1A2 (0.44) CYP2A6CYP1A2ALDH1A1TRPA1TSHR
SCHEMBL29707612 0.87 CYP1A2 (0.44) CYP2A6CYP1A2ALDH1A1TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101080821-A Organic thin-film transistor and method for manufacturing same SHARP KK (JP) 2007-11-28 CN disclosed