Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL27927236 | 0.98 | TSHR (0.50) | TSHRALDH1A1SLC6A4SLC6A3CES2 | |
| Chlorobenzene SCHEMBL27598201 | 0.94 | TSHR (0.46) | TSHRALDH1A1SLC6A4SLC6A3CES2 | |
| Chlorobenzene SCHEMBL28284822 | 0.86 | TSHR (0.52) | TSHRALDH1A1SLC6A4SLC6A3CES2 | |
| Chlorobenzene SCHEMBL28020888 | 0.86 | TSHR (0.52) | TSHRALDH1A1SLC6A4SLC6A3CES2 | |
| Chlorobenzene SCHEMBL28280157 | 0.86 | TSHR (0.52) | TSHRALDH1A1SLC6A4SLC6A3CES2 | |
| Chlorobenzene SCHEMBL2830970 | 0.85 | TSHR (0.65) | TSHRALDH1A1CES2CES1KMT2A | |
| Chlorobenzene SCHEMBL27741176 | 0.85 | TSHR (0.65) | TSHRALDH1A1CES2CES1KMT2A | |
| Chlorobenzene SCHEMBL4166598 | 0.85 | TSHR (0.65) | TSHRALDH1A1CES2CES1KMT2A | |
| Chlorobenzene SCHEMBL28097396 | 0.84 | TSHR (0.50) | TSHRALDH1A1SLC6A4SLC6A3CES2 | |
| Acetic Acid Methyl Ester SCHEMBL837627 | 0.84 | MEN1 (0.50) | ALDH1A1SLC6A3KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033006-B | Preparation method of diaryl ketone | 长沙理工大学 | 2018-12-18 | — | — | CN | claimed |
| CN-108246099-A | Automobile indoor VOC remover and preparation method thereof | 段宝荣 | 2018-07-06 | — | — | CN | claimed |
| CN-107266350-A | A kind of fragrant acetic acid of adjacent halogen（Ester）The method for preparing the ketone compounds of indoline 2 in aqueous phase with amine | 长沙理工大学 | 2017-10-20 | — | — | CN | claimed |
| CN-107033006-A | Preparation method of diaryl ketone | 长沙理工大学 | 2017-08-11 | — | — | CN | claimed |
| CN-104478896-B | The preparation method of a kind of high purity clopidogrel and salt thereof | HUIZHOU XINLITAI PHARMACEUTICAL CO., LTD. (CN) | 2016-01-06 | — | — | CN | claimed |
| CN-104370732-B | The preparation method of a kind of clopidogrel and intermediate thereof | SHANDONG XINLITAI PHARMACEUTICAL CO., LTD. (CN) | 2015-08-19 | — | — | CN | claimed |
| CN-104478896-A | Preparation method of high-purity clopidogrel and salt of clopidogrel | HUIZHOU XINLITAI PHARMACEUTICAL CO LTD | 2015-04-01 | — | — | CN | claimed |
| CN-104370732-A | Clopidogrel and clopidogrel intermediate preparation method | SHANDONG SALUBRIS PHARMACEUTICALS CO LTD | 2015-02-25 | — | — | CN | claimed |
| CN-103450005-A | Preparation method of clopidogrel and intermediates thereof, namely alpha-bromo-o-clorophenylacetic acid and alpha-thiophene ethylamine substituted acetate silicate | SHENZHEN SALUBRIS PHARM CO LTD | 2013-12-18 | — | — | CN | claimed |
| CN-103387497-A | Preparation methods for clopidogrel and its intermediates--methyl alpha-bromo-2-chloro-phenylacetate and thiophene ethylamino-substituted methyl acetate | SHENZHEN SALUBRIS PHARM CO LTD | 2013-11-13 | — | — | CN | claimed |
| CN-102001983-B | Preparation method of 5-(2-bromine-propiono)-2-thiophenyl phenyleacetic acid ester | HENAN INST OF BUSINESS SCIENCE CO LTD | 2013-02-20 | — | — | CN | claimed |
| CN-101585842-B | Research and control method of impurity B control method in clopidogrel | BEIJING SECOND PHARMACEUTICAL CO LTD | 2011-07-20 | — | — | CN | claimed |
| CN-102001983-A | Preparation method of 5-(2-bromine-propiono)-2-thiophenyl phenyleacetic acid ester | HENAN INST OF BUSINESS SCIENCE CO LTD | 2011-04-06 | — | — | CN | claimed |
| CN-101033207-B | Method of preparing 2-thiophenyl-5-propionyl phenyl acetic acid | NINGBO ZHIHUA CHEMISTRY CO LTD | 2010-08-18 | — | — | CN | claimed |
| CN-101774914-A | Method for synthesizing methyl alpha-bromo-2-chlorophenylacetate | TIANJIN CENTRAL PHARMACEUTICAL | 2010-07-14 | — | — | CN | claimed |
| CN-101585842-A | Research and control method of impurity B control method in clopidogrel | BEIJING SECOND PHARMACEUTICAL (CN) | 2009-11-25 | — | — | CN | claimed |
| CN-101033207-A | Method of preparing 2-thiophenyl-5-propionyl phenyl acetic acid | NINGBO ZHIHUA CHEMISTRY CO LTD (CN) | 2007-09-12 | — | — | CN | claimed |
| CN-110003271-A | The preparation method of aromatic compound | 住友化学株式会社 | 2019-07-12 | — | — | CN | disclosed |
| CN-1986542-A | Preparing process of 2-(10-oxy-10,11-dihydrodibenz [b,f]-thiotropilium-2-yl) propionic acid | KANGRUI CHEMICAL CO LTD CHANGZ (CN) | 2007-06-27 | — | — | CN | disclosed |
| CN-1986528-A | Preparing process of 5-propionyl-2-thiophenyl phenylacetate | KANGRUI CHEMICAL CO LTD CHANGZ (CN) | 2007-06-27 | — | — | CN | disclosed |