Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27686557 | 1.00 | CYP3A4 (0.58) | CYP3A4ESR1ESR2POLBHCAR2 | |
| SCHEMBL689426 | 0.93 | CYP3A4 (0.66) | CYP3A4ESR1ESR2POLBMEN1 | |
| SCHEMBL689425 | 0.93 | CYP3A4 (0.66) | CYP3A4ESR1ESR2POLBMEN1 | |
| SCHEMBL689595 | 0.93 | CYP3A4 (0.66) | CYP3A4ESR1ESR2POLBMEN1 | |
| Phenyl Fumarate SCHEMBL28538092 | 0.85 | HCAR2 (0.53) | ESR1ESR2HCAR2MEN1KMT2A | |
| SCHEMBL8401389 | 0.84 | CYP3A4 (0.56) | CYP3A4ESR1ESR2POLBMEN1 | |
| SCHEMBL29331106 | 0.84 | CYP3A4 (0.61) | CYP3A4ESR1ESR2POLBHCAR2 | |
| SCHEMBL14800036 | 0.82 | KDM4E (0.59) | POLBHCAR2MEN1KMT2AKDM4E | |
| Phenyl Fumarate SCHEMBL528592 | 0.81 | HCAR2 (0.55) | HCAR2MEN1KMT2AKDM4EALDH1A1 | |
| Phenyl Fumarate SCHEMBL529210 | 0.81 | HCAR2 (0.55) | HCAR2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101076457-B | Pneumatic tire | BRIDGESTONE CORP | 2011-07-27 | — | — | CN | disclosed |
| CN-101076457-A | Pneumatic tire | BRIDGESTONE CORP (JP) | 2007-11-21 | — | — | CN | disclosed |