Acetic Acid

Acetic Acid

SCHEMBL27689136

CC(=O)O.O=C(Cl)CCl

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29021405 0.89
Acetone SCHEMBL28279591 0.89
SCHEMBL28175986 0.86
Methyl Alcohol SCHEMBL27979683 0.85
SCHEMBL1332028 0.84
SCHEMBL27679189 0.84 TSHR (0.54)
SCHEMBL1331137 0.84
SCHEMBL1331358 0.84
SCHEMBL9584 0.84
Acetamide SCHEMBL5315073 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-208071616-U Cyclic phosphonic acid anhydrides recycle preparation facilities 利尔化学股份有限公司 2018-11-09 CN disclosed
CN-108373485-A A kind of production method and device of cyclic phosphonic acid anhydrides 利尔化学股份有限公司 2018-08-07 CN disclosed
CN-104649887-B Production method of chloroacetic acid and method for recovering catalysts in production process of chloroacetic acid 中国天辰工程有限公司 2017-05-03 CN disclosed
CN-102762204-B Inhibitors of hematopoietic cell kinase (P59-HCK) and their use in the treatment of influenza infections RESPIVERT LTD 2014-11-19 CN disclosed
CN-101386574-B Method for preparing chloracetic acid using acetyl chloride as catalyst ZHANG TIANDE 2013-01-23 CN disclosed
CN-102762204-A Inhibitors of hematopoietic cell kinase (P59-HCK) and their use in the treatment of influenza infections RESPIVERT LTD 2012-10-31 CN disclosed
CN-101386574-A Method for preparing chloracetic acid using acetyl chloride as catalyst TIANDE ZHANG (CN) 2009-03-18 CN disclosed
CN-101065148-A Conjugated complement cascade inhibitors DIMENSIONAL PHARM INC (US) 2007-10-31 CN disclosed