Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 8/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | G6PD | P11413 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30363708 | 0.87 | NQO2 (0.88) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL3731976 | 0.87 | NQO2 (0.88) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL27897957 | 0.87 | NQO2 (0.62) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL6034058 | 0.85 | NQO2 (0.61) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL13439501 | 0.85 | NQO2 (0.84) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL1513023 | 0.82 | NQO2 (1.00) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL7868972 | 0.80 | NQO2 (0.47) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL18387578 | 0.80 | NQO2 (0.69) | NQO2MAPTRAB9APOLBNPC1 | |
| Hydrochloric Acid SCHEMBL28752582 | 0.80 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 | |
| Hydrogen Sulfide SCHEMBL28130030 | 0.80 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101068808-A | 1- [ (6, 7-substituted-2-alkoxyquinoxalin-3-yl) aminocarbonyl ] -4- (hetero) arylpiperazine derivatives | REXAHN PHARMACEUTICALS INC (US) | 2007-11-07 | — | — | CN | disclosed |