Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 19/20 | 0.81 |
| ▸ | IGF1R | P08069 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696821 | 1.00 | NTRK1 (0.81) | NTRK1IGF1RJAK2 | |
| SCHEMBL4696858 | 1.00 | NTRK1 (0.81) | NTRK1IGF1RJAK2 | |
| SCHEMBL3772425 | 0.89 | NTRK1 (1.00) | NTRK1JAK2 | |
| SCHEMBL3812515 | 0.89 | NTRK1 (1.00) | NTRK1JAK2 | |
| SCHEMBL3779322 | 0.88 | NTRK1 (1.00) | NTRK1JAK2 | |
| SCHEMBL3705689 | 0.88 | NTRK1 (0.68) | NTRK1 | |
| SCHEMBL27709595 | 0.88 | NTRK1 (0.68) | NTRK1 | |
| SCHEMBL57380 | 0.87 | NTRK1 (0.62) | NTRK1IGF1RJAK2 | |
| SCHEMBL4750903 | 0.86 | NTRK1 (0.79) | NTRK1JAK2 | |
| SCHEMBL56800 | 0.86 | NTRK1 (0.79) | NTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101119988-A | Chemical compound | ASTRAZENECA AB (SE) | 2008-02-06 | — | — | CN | disclosed |