Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.56 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.56 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.56 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2022441 | 0.85 | MAP2K1 (0.54) | MAP2K1MAP2K2PRKCZIARS2MAPT | |
| SCHEMBL2023622 | 0.84 | MAP2K1 (0.58) | MAP2K1MAP2K2PRKCZIARS2MAPT | |
| SCHEMBL3885464 | 0.81 | MAP2K1 (0.60) | MAP2K1MAP2K2PRKCZIARS2ALDH1A1 | |
| SCHEMBL29781369 | 0.81 | MAP2K1 (0.60) | MAP2K1MAP2K2PRKCZIARS2ALDH1A1 | |
| SCHEMBL2021884 | 0.80 | MAP2K1 (0.67) | MAP2K1MAP2K2PRKCZIARS2 | |
| SCHEMBL28766210 | 0.80 | MAP2K1 (0.67) | MAP2K1MAP2K2PRKCZIARS2 | |
| SCHEMBL2025345 | 0.79 | MAP2K1 (0.67) | MAP2K1MAP2K2PRKCZIARS2 | |
| SCHEMBL2023267 | 0.79 | MAP2K1 (0.69) | MAP2K1MAP2K2PRKCZIARS2 | |
| SCHEMBL31354759 | 0.79 | MAP2K1 (0.62) | MAP2K1MAP2K2PRKCZIARS2 | |
| SCHEMBL2018997 | 0.79 | MAP2K1 (0.53) | MAP2K1MAP2K2PRKCZIARS2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101065358-A | 3-arylamino pyridine derivatives | APPLIED RESEARCH SYSTEMS (AN) | 2007-10-31 | — | — | CN | disclosed |