Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 9/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27636316 | 0.91 | TPMT (0.48) | HCAR1TPMTF10MAPTKMT2A | |
| SCHEMBL142916 | 0.80 | MEN1 (0.54) | F10MAPTKMT2AALDH1A1TDP1 | |
| SCHEMBL505240 | 0.78 | CA12 (0.53) | F10TDP1HTT | |
| Hydrochloric Acid SCHEMBL4747459 | 0.77 | CA12 (0.51) | F10TDP1HTT | |
| SCHEMBL27749289 | 0.77 | EP300 (0.37) | TPMTF10MAPTKMT2AKDM4E | |
| SCHEMBL92819 | 0.73 | KDM4E (0.57) | F10MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28025799 | 0.72 | NOTUM (0.44) | F10MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL17059032 | 0.71 | COMT (0.49) | HCAR1MAPTKDM4EALDH1A1SMN1; SMN2 | |
| Benzene SCHEMBL27458637 | 0.71 | TPMT (0.84) | HCAR1TPMTMAPTKDM4EALDH1A1 | |
| SCHEMBL6049982 | 0.71 | KMT2A (0.53) | F10MAPTKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484167-B | The use of derviate of pyridone for preventing and treating radioactive injury of lungs | SHANGHAI GENOMICS INC | 2012-07-04 | — | — | CN | disclosed |
| CN-101484167-A | The use of derviate of pyridone for preventing and treating radioactive injury of lungs | SHANGHAI GENOMICS INC (CN) | 2009-07-15 | — | — | CN | disclosed |
| CN-100358872-C | The derivatives of pyridone and use thereof | SHANGHAI GENOMICS INC (CN) | 2008-01-02 | — | — | CN | disclosed |