Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | GUSB | P08236 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30000230 | 0.92 | AR (0.75) | ARMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL30384316 | 0.84 | AR (0.78) | ARMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL10830021 | 0.84 | AR (1.00) | ARMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL11050763 | 0.84 | AR (1.00) | ARMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL25266016 | 0.84 | AR (0.78) | ARMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL25202088 | 0.84 | AR (0.78) | ARMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL5138775 | 0.84 | AR (0.63) | ARMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL5138776 | 0.84 | AR (0.63) | ARMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL5088647 | 0.83 | MAPT (0.62) | ARMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL5088653 | 0.83 | MAPT (0.62) | ARMAPTKMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101143861-A | B ring 4'-single substituted flavone compounds, preparation method and use | SHANGHAI INST MATERIA MEDICA (CN) | 2008-03-19 | — | — | CN | disclosed |