Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091752 | 0.93 | CRACR2A (0.41) | ALDH1A1HTTPOLBMAPTRAB9A | |
| SCHEMBL27697205 | 0.86 | MEN1 (0.48) | ALDH1A1HTTMEN1KMT2ATDP1 | |
| SCHEMBL27717256 | 0.85 | MEN1 (0.47) | ALDH1A1HTTMEN1KMT2ATDP1 | |
| SCHEMBL27717099 | 0.84 | MEN1 (0.53) | ALDH1A1HTTMEN1KMT2ATDP1 | |
| SCHEMBL27717233 | 0.84 | MAPT (0.52) | ALDH1A1HTTMEN1KMT2ATDP1 | |
| SCHEMBL27717098 | 0.84 | TLR8 (0.48) | ALDH1A1HTTPOLBMEN1KMT2A | |
| SCHEMBL27697208 | 0.83 | MEN1 (0.49) | ALDH1A1HTTMEN1KMT2ATDP1 | |
| SCHEMBL27717122 | 0.81 | KDR (0.52) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL15000677 | 0.80 | EGFR (0.43) | ALDH1A1HTTPOLBMEN1KMT2A | |
| SCHEMBL2094427 | 0.79 | CRACR2A (0.42) | ALDH1A1HTTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101083985-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2007-12-05 | — | — | CN | claimed |
| CN-101083985-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2007-12-05 | — | — | CN | disclosed |