Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909144 | 0.86 | SMN1; SMN2 (0.48) | CYP1A2CYP2D6CYP2C19MAPTLMNA | |
| SCHEMBL4904612 | 0.82 | SMN1; SMN2 (0.47) | CYP1A2CYP2D6CYP2C19MAPTLMNA | |
| SCHEMBL4899071 | 0.82 | MAPT (0.54) | CYP1A2CYP2D6CYP2C19MAPTLMNA | |
| SCHEMBL27699241 | 0.81 | KDM4E (0.55) | CYP1A2CYP2D6CYP2C19MAPTLMNA | |
| SCHEMBL4908756 | 0.80 | MAPT (0.49) | CYP1A2CYP2D6CYP2C19MAPTLMNA | |
| SCHEMBL27685335 | 0.80 | KMT2A (0.46) | CYP1A2CYP2D6CYP2C19MAPTLMNA | |
| SCHEMBL4909961 | 0.79 | MAPT (0.48) | CYP1A2CYP2D6CYP2C19MAPTLMNA | |
| SCHEMBL4910266 | 0.79 | MAPT (0.48) | CYP1A2CYP2D6CYP2C19MAPTLMNA | |
| SCHEMBL4909447 | 0.77 | MAPT (0.46) | CYP1A2CYP2D6CYP2C19MAPTLMNA | |
| SCHEMBL27548146 | 0.77 | CYP1A2 (0.46) | CYP1A2CYP2D6CYP2C19MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101056631-A | Derivatives of aryl (or heteroaryl) azolylcarbinols (in particular cizolirtin citrate) for the treatment of opioid addiction | ESTEVE LABOR DR (ES) | 2007-10-17 | — | — | CN | claimed |
| CN-101031291-A | Compound containing methanol and composition containing at least one nsaid active substance | ESTEVE LABOR DR (ES) | 2007-09-05 | — | — | CN | claimed |
| CN-101056631-A | Derivatives of aryl (or heteroaryl) azolylcarbinols (in particular cizolirtin citrate) for the treatment of opioid addiction | ESTEVE LABOR DR (ES) | 2007-10-17 | — | — | CN | disclosed |
| CN-101031291-A | Compound containing methanol and composition containing at least one nsaid active substance | ESTEVE LABOR DR (ES) | 2007-09-05 | — | — | CN | disclosed |