SCHEMBL27697382

SCHEMBL27697382

[CH2]CC(C(=O)O)C1CCNCC1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 6/20 0.67
CPB2 Q96IY4 6/20 0.67
GABRA5 P31644 3/20 0.40
GABRB2 P47870 3/20 0.40
GABRA1 P14867 2/20 0.40
GABRA4 P48169 2/20 0.40
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
TSHR P16473 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRE P78334 1/20 0.40
PMP22 Q01453 1/20 0.40
GABRA6 Q16445 1/20 0.40
GABRG1 Q8N1C3 1/20 0.40
GABRG3 Q99928 1/20 0.40
GABRQ Q9UN88 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27678545 1.00 CPN1 (0.67) CPN1CPB2GABRA5GABRB2GABRA1
SCHEMBL8969105 0.80 CPN1 (0.67) CPN1CPB2GABRA5GABRB2GABRA1
SCHEMBL1775857 0.80 CPN1 (0.67) CPN1CPB2GABRA5GABRB2GABRA1
SCHEMBL2353967 0.80 CPN1 (1.00) CPN1CPB2GABRA5GABRB2GABRA1
Hydrochloric Acid SCHEMBL910525 0.78 CPN1 (0.65) CPN1CPB2GABRA5GABRB2GABRA1
SCHEMBL28301971 0.77 CPN1 (0.62) CPN1CPB2GABRA5GABRB2GABRA1
SCHEMBL28763756 0.77 SLC6A2 (0.45) CPN1CPB2OPRD1
SCHEMBL27697385 0.77 SLC6A2 (0.45) CPN1CPB2OPRD1
Piperidine SCHEMBL3443987 0.74 CPN1 (0.59) CPN1CPB2GABRA5GABRB2GABRA1
SCHEMBL4431618 0.74 CPN1 (0.42) CPN1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-85105066-A The production of condensed seven-membered compounds, their and application 1986-12-31 CN disclosed