Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 16/20 | 0.66 |
| ▸ | PTGER2 | P43116 | 13/20 | 0.66 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27697785 | 0.93 | PTGER4 (0.67) | PTGER4PTGER2PTGER3KMT2AMEN1 | |
| SCHEMBL27856603 | 0.85 | PTGER4 (0.64) | PTGER4PTGER2GAA | |
| SCHEMBL4085414 | 0.84 | PTGER4 (0.92) | PTGER4PTGER2PTGER3 | |
| SCHEMBL4077758 | 0.84 | PTGER4 (0.64) | PTGER4PTGER2PTGER3KMT2AMEN1 | |
| SCHEMBL4077394 | 0.84 | PTGER4 (0.66) | PTGER4PTGER2PTGER3KMT2AMEN1 | |
| SCHEMBL27718120 | 0.84 | PTGER4 (0.58) | PTGER4PTGER2PTGER3KMT2A | |
| SCHEMBL27873338 | 0.84 | PTGER4 (0.68) | PTGER4PTGER2PTGER3 | |
| SCHEMBL4077760 | 0.83 | PTGER4 (0.82) | PTGER4PTGER2 | |
| SCHEMBL4081976 | 0.83 | PTGER4 (0.72) | PTGER4PTGER2PTGER3 | |
| SCHEMBL4087462 | 0.83 | PTGER4 (0.69) | PTGER4PTGER2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101133037-B | Six-membered heterocyclic compound and use thereof | ASAHI KASEI PHARMA CORP | 2012-05-09 | — | — | CN | disclosed |
| CN-101133037-A | Six-membered heterocyclic compound and use thereof | ASAHI KASEI PHARMA CORP (JP) | 2008-02-27 | — | — | CN | disclosed |