Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698329 | 0.92 | GRM1 (0.44) | GRM1MAPTMCHR1XDHMEN1 | |
| SCHEMBL1688960 | 0.90 | GRM1 (0.50) | GRM1MAPTMCHR1XDHMEN1 | |
| SCHEMBL4516045 | 0.89 | GRM1 (0.41) | GRM1MAPTMCHR1XDHMEN1 | |
| SCHEMBL1689106 | 0.88 | GRM1 (0.44) | GRM1MAPTMCHR1XDHKMT2A | |
| SCHEMBL1689332 | 0.87 | GRM1 (0.48) | GRM1MAPTMCHR1XDHMEN1 | |
| SCHEMBL1689013 | 0.87 | GRM1 (0.50) | GRM1MAPTMCHR1XDHMEN1 | |
| SCHEMBL1689015 | 0.85 | MAPT (0.44) | GRM1MAPTMCHR1XDHKMT2A | |
| SCHEMBL1753607 | 0.85 | NPSR1 (0.45) | GRM1MAPTMCHR1XDHMEN1 | |
| SCHEMBL1753604 | 0.85 | MAPT (0.46) | GRM1MAPTMCHR1XDHUSP2 | |
| SCHEMBL1689027 | 0.84 | MAPT (0.43) | GRM1MAPTMCHR1XDHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102241680-A | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC | 2011-11-16 | — | — | CN | claimed |
| CN-101048408-A | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC (BM) | 2007-10-03 | — | — | CN | claimed |
| CN-102241680-A | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC | 2011-11-16 | — | — | CN | disclosed |
| CN-101048408-B | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC | 2011-07-06 | — | — | CN | disclosed |
| CN-101048408-A | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC (BM) | 2007-10-03 | — | — | CN | disclosed |