Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.81 |
| ▸ | HTT | P42858 | 5/20 | 0.81 |
| ▸ | HPGD | P15428 | 4/20 | 0.81 |
| ▸ | PKM | P14618 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.81 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | GFER | P55789 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980968 | 0.85 | MAPT (0.82) | MAPTHTTHPGDPKMALOX15 | |
| SCHEMBL3388184 | 0.85 | GAA (1.00) | MAPTHTTHPGDPKMALOX15 | |
| SCHEMBL3388187 | 0.84 | KDM4E (1.00) | MAPTHTTHPGDPKMALOX15 | |
| SCHEMBL12334438 | 0.82 | HTT (0.70) | MAPTHTTHPGDPKMALOX15 | |
| SCHEMBL3821064 | 0.81 | KMT2A (1.00) | MAPTHTTHPGDPKMALOX15 | |
| SCHEMBL29059277 | 0.81 | KDM4E (0.76) | MAPTHTTHPGDPKMALOX15 | |
| SCHEMBL1407609 | 0.81 | MAPT (0.58) | MAPTHTTHPGDPKMALOX15 | |
| SCHEMBL13051739 | 0.80 | HTT (0.66) | MAPTHTTHPGDPKMALOX15 | |
| SCHEMBL1717541 | 0.76 | MAPT (0.65) | MAPTHTTHPGDPKMALOX15 | |
| SCHEMBL12873725 | 0.76 | GAA (0.68) | MAPTHTTHPGDPKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101027051-A | Methods for treating hepatitis C | PTC THERAPEUTICS INC (US) | 2007-08-29 | — | — | CN | disclosed |