Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825134 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHROPRM1OPRD1ALDH1A1 | |
| SCHEMBL2829429 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2TSHROPRM1OPRD1ALDH1A1 | |
| SCHEMBL2828619 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2TSHROPRM1OPRD1ALDH1A1 | |
| SCHEMBL2830926 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHROPRM1OPRD1ALDH1A1 | |
| SCHEMBL2829489 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHROPRM1OPRD1ALDH1A1 | |
| SCHEMBL2827014 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHROPRM1OPRD1ALDH1A1 | |
| SCHEMBL2829550 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHROPRM1OPRD1ALDH1A1 | |
| SCHEMBL2830858 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHROPRM1OPRD1ALDH1A1 | |
| SCHEMBL2827704 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHROPRM1OPRD1ALDH1A1 | |
| SCHEMBL2831457 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHROPRM1OPRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048158-A | Thiazole based inhibitors of ATP-utilizing enyzmes | GENENTECH INC (US) | 2007-10-03 | — | — | CN | disclosed |