Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27719992 | 0.92 | PTGER4 (0.37) | PTGER4TRPV1KCNH2PDE2A | |
| SCHEMBL13685551 | 0.85 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL1474311 | 0.85 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL12827636 | 0.79 | PTGER4 (0.36) | PTGER4KCNH2PDE2A | |
| SCHEMBL1474664 | 0.79 | TRPV1 (0.39) | PTGER4TRPV1 | |
| SCHEMBL27699466 | 0.77 | HPGD (0.33) | TRPV1PDE2A | |
| SCHEMBL12827781 | 0.74 | PTGER4 (0.38) | PTGER4KCNH2PDE2A | |
| SCHEMBL27699465 | 0.73 | PDE2A (0.37) | TRPV1PDE2A | |
| SCHEMBL1474443 | 0.72 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL27699471 | 0.72 | TRPV1 (0.41) | TRPV1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160285-A | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as vr1 receptor antagonists | PFIZER (US) | 2008-04-09 | — | — | CN | claimed |