SCHEMBL27699640

SCHEMBL27699640

Cc1c(Oc2ccc([N+](=O)[O-])cc2)cc(C(=O)O)c(C)c1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
AKR1C3 P42330 1/20 0.48
AKR1C2 P52895 1/20 0.48
KDM4E B2RXH2 2/20 0.48
SRD5A2 P31213 1/20 0.48
MAPT P10636 2/20 0.46
NPC1 O15118 1/20 0.46
MAPK1 P28482 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MYOC Q99972 1/20 0.46
CTSV O60911 1/20 0.45
CTSL P07711 1/20 0.45
HTT P42858 1/20 0.45
GAA P10253 1/20 0.44
PKM P14618 1/20 0.44
HSPB1 P04792 1/20 0.44
HPSE Q9Y251 1/20 0.43
FFAR1 O14842 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10895049 0.81 AKR1C3 (0.44) MEN1KMT2AAKR1C3AKR1C2KDM4E
SCHEMBL9350045 0.80 PHLPP2 (0.41) KDM4EGAAALDH1A1
SCHEMBL9350049 0.79 POLB (0.39) GAAALDH1A1
SCHEMBL10896433 0.77 HAO1 (0.41) KDM4ENPC1MAPK1RAB9AGAA
SCHEMBL25406283 0.75 MEN1 (0.50) MEN1KMT2AAKR1C3AKR1C2KDM4E
SCHEMBL30298699 0.75 MEN1 (0.50) MEN1KMT2AAKR1C3AKR1C2KDM4E
SCHEMBL31557883 0.75 MEN1 (0.60) MEN1KMT2AAKR1C3AKR1C2KDM4E
SCHEMBL31557914 0.75 MEN1 (0.60) MEN1KMT2AAKR1C3AKR1C2KDM4E
SCHEMBL4452102 0.75 KMT2A (0.55) MEN1KMT2AKDM4ESRD5A2MAPT
SCHEMBL10894601 0.73 POLB (0.35) KDM4ENPC1RAB9AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101128514-B Benzoxazole resin precursor, polybenzoxazole resin, resin film and semiconductor device SUMITOMO BAKELITE CO 2011-05-25 CN disclosed
CN-101128514-A Benzoxazole resin precursor, polybenzoxazole resin, resin film and semiconductor device SUMITOMO BAKELITE CO (JP) 2008-02-20 CN disclosed