Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001978 | 0.91 | EPAS1 (0.41) | ALDH1A1MBTD1L3MBTL3EPAS1L3MBTL1 | |
| SCHEMBL22001816 | 0.91 | EPAS1 (0.41) | ALDH1A1MBTD1L3MBTL3EPAS1L3MBTL1 | |
| SCHEMBL21307178 | 0.91 | EPAS1 (0.41) | ALDH1A1MBTD1L3MBTL3EPAS1L3MBTL1 | |
| SCHEMBL23085711 | 0.91 | EPAS1 (0.41) | ALDH1A1MBTD1L3MBTL3EPAS1L3MBTL1 | |
| SCHEMBL20999161 | 0.91 | EPAS1 (0.41) | ALDH1A1MBTD1L3MBTL3EPAS1L3MBTL1 | |
| SCHEMBL24267259 | 0.91 | EPAS1 (0.41) | ALDH1A1MBTD1L3MBTL3EPAS1L3MBTL1 | |
| SCHEMBL21491117 | 0.91 | EPAS1 (0.41) | ALDH1A1MBTD1L3MBTL3EPAS1L3MBTL1 | |
| SCHEMBL24622814 | 0.91 | EPAS1 (0.41) | ALDH1A1MBTD1L3MBTL3EPAS1L3MBTL1 | |
| SCHEMBL22506806 | 0.91 | EPAS1 (0.41) | ALDH1A1MBTD1L3MBTL3EPAS1L3MBTL1 | |
| SCHEMBL22217255 | 0.91 | EPAS1 (0.41) | ALDH1A1MBTD1L3MBTL3EPAS1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101553472-A | Tetrahydronaphthaline derivatives, methods for the production and use thereof as anti-inflammatory agents | BAYER SCHERING PHARMA AG (DE) | 2009-10-07 | — | — | CN | disclosed |
| CN-101495471-A | Novel indol-pyrrol derivatives for the treatment of proliferative and inflammatory diseases | SCHEBO BIOTECH AG (DE) | 2009-07-29 | — | — | CN | disclosed |
| CN-101479244-A | New urea derivatives and the application thereof | SCHEBO BIOTECH AG (DE) | 2009-07-08 | — | — | CN | disclosed |
| CN-101160305-A | Substituted chroman derivatives, method for the production and the use thereof in the form of antiphlogistics | SCHERING AG (DE) | 2008-04-09 | — | — | CN | disclosed |