Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Phenylethyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.46 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.94 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylethyl Alcohol SCHEMBL8968173 | 0.97 | TDP1 (1.00) | TDP1TSHRCA2ALDH1A1HPGD | |
| Phenylethyl Alcohol SCHEMBL27927126 | 0.97 | TDP1 (1.00) | TDP1TSHRCA2ALDH1A1HPGD | |
| Phenylethyl Alcohol SCHEMBL28820852 | 0.97 | TDP1 (1.00) | TDP1TSHRCA2ALDH1A1HPGD | |
| Phenylethyl Alcohol SCHEMBL11450063 | 0.97 | TDP1 (1.00) | TDP1TSHRCA2ALDH1A1HPGD | |
| Phenylethyl Alcohol SCHEMBL1838 | 0.97 | — | — | |
| Phenylethyl Alcohol SCHEMBL1867158 | 0.97 | TDP1 (1.00) | TDP1TSHRCA2ALDH1A1HPGD | |
| Phenylethyl Alcohol SCHEMBL5967453 | 0.94 | TDP1 (0.94) | TDP1TSHRCA2ALDH1A1HPGD | |
| Phenylethyl Alcohol SCHEMBL10363032 | 0.94 | TDP1 (0.94) | TDP1TSHRCA2ALDH1A1HPGD | |
| Phenylethyl Alcohol SCHEMBL5946545 | 0.94 | TDP1 (0.94) | TDP1TSHRCA2ALDH1A1HPGD | |
| Phenylethyl Alcohol SCHEMBL29880294 | 0.94 | TDP1 (0.94) | TDP1TSHRCA2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130791-A | A process to produce an enrichment feed | EASTMAN CHEM CO | 2015-12-09 | — | — | CN | disclosed |
| CN-101189207-B | A process to produce an enriched composition through the use of a catalyst removal zone and an enrichment zone | EASTMAN CHEM CO | 2012-11-14 | — | — | CN | disclosed |
| CN-101248035-B | An enriched terephthalic acid composition | GRUPO PETROTEMEX SA DE CV | 2012-08-15 | — | — | CN | disclosed |
| CN-101180253-B | Process to produce an enriched composition | EASTMAN CHEM CO | 2012-07-11 | — | — | CN | disclosed |
| CN-101287696-B | A process to enrich a carboxylic acid composition | EASTMAN CHEM CO | 2012-06-27 | — | — | CN | disclosed |
| CN-101180254-B | Process to produce a post catalyst removal composition | EASTMAN CHEM CO | 2011-07-13 | — | — | CN | disclosed |
| CN-101553457-A | Process for preparing an enrichment feed | EASTMAN CHEM CO (US) | 2009-10-07 | — | — | CN | disclosed |
| CN-101287696-A | A process to enrich a carboxylic acid composition | EASTMAN CHEM CO (US) | 2008-10-15 | — | — | CN | disclosed |
| CN-101248035-A | An enriched terephthalic acid composition | EASTMAN CHEM CO (US) | 2008-08-20 | — | — | CN | disclosed |
| CN-101189207-A | A process to produce an enriched composition through the use of a catalyst removal zone and an enrichment zone | EASTMAN CHEM CO (US) | 2008-05-28 | — | — | CN | disclosed |
| CN-101184719-A | An enrichment process using compounds useful in a polyester process | EASTMAN CHEM CO (US) | 2008-05-21 | — | — | CN | disclosed |
| CN-101180254-A | Process to produce a post catalyst removal composition | EASTMAN CHEM CO (US) | 2008-05-14 | — | — | CN | disclosed |
| CN-101180253-A | Process to produce an enriched composition | EASTMAN CHEM CO (US) | 2008-05-14 | — | — | CN | disclosed |
| CN-101175710-A | An enriched isophthalic acid composition | EASTMAN CHEM CO (US) | 2008-05-07 | — | — | CN | disclosed |