Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 14/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810920 | 0.92 | BCHE (0.61) | BCHEHDAC3HDAC1HDAC2KCNA3 | |
| SCHEMBL27709635 | 0.87 | BCHE (0.59) | BCHEHDAC3HDAC1HDAC2KCNA3 | |
| SCHEMBL27742584 | 0.86 | F2 (0.63) | BCHEHDAC3HDAC1HDAC2KCNA3 | |
| SCHEMBL27652150 | 0.86 | HDAC3 (0.60) | BCHEHDAC3HDAC1HDAC2KCNA3 | |
| SCHEMBL27630590 | 0.85 | HDAC3 (0.62) | BCHEHDAC3HDAC1HDAC2KCNA3 | |
| Hydrochloric Acid SCHEMBL28025410 | 0.85 | BCHE (0.51) | BCHEHDAC3HDAC1HDAC2KCNA3 | |
| SCHEMBL28356282 | 0.84 | F2 (0.46) | BCHEHDAC3HDAC1HDAC2KCNA3 | |
| SCHEMBL28896375 | 0.83 | F2 (0.51) | BCHEHDAC3HDAC1HDAC2KCNA3 | |
| Hydrochloric Acid SCHEMBL28353177 | 0.83 | F2 (0.46) | BCHEHDAC3HDAC1HDAC2KCNA3 | |
| SCHEMBL31352296 | 0.82 | BCHE (0.49) | BCHEHDAC3HDAC1HDAC2KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103339110-A | Substituted hetero-biaryl compounds as CDK9 inhibitors and uses thereof | NOVARTIS AG | 2013-10-02 | — | — | CN | disclosed |
| CN-103298787-A | 3-(aminoaryl)-pyridine compounds | NOVARTIS AG | 2013-09-11 | — | — | CN | disclosed |
| CN-101035795-B | Thiazolyl dihydroindazoles | BOEHRINGER INGELHEIM INT | 2012-03-21 | — | — | CN | disclosed |
| CN-101035795-A | Thiazolyl dihydroindazoles | BOEHRINGER INGELHEIM INT (DE) | 2007-09-12 | — | — | CN | disclosed |