Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | BTK | Q06187 | 11/20 | 0.39 |
| ▸ | CMKLR1 | Q99788 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027938 | 0.82 | ESR1 (0.61) | ESR1BTKCMKLR1EGFR | |
| SCHEMBL4031427 | 0.81 | ESR1 (0.65) | ESR1BTKCMKLR1EGFR | |
| SCHEMBL4030883 | 0.79 | ESR1 (0.68) | ESR1BTKCMKLR1EGFR | |
| SCHEMBL4029342 | 0.78 | ESR1 (0.69) | ESR1BTKCMKLR1EGFR | |
| SCHEMBL4027998 | 0.77 | ESR1 (0.49) | ESR1BTKCMKLR1 | |
| SCHEMBL5414144 | 0.76 | ESR1 (0.52) | ESR1BTKCMKLR1EGFR | |
| SCHEMBL4028037 | 0.75 | ESR1 (0.61) | ESR1BTKCMKLR1EGFR | |
| SCHEMBL27573477 | 0.73 | ESR1 (0.45) | ESR1BTK | |
| SCHEMBL27573478 | 0.73 | ESR1 (0.45) | ESR1BTK | |
| SCHEMBL4031188 | 0.73 | ESR1 (0.72) | ESR1BTKCMKLR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101054364-A | Substituted 4-(indazol-3-yl)phenols as estrogen receptor (ER) ligands and their use in the treatmentof inflammarory diseases | WYETH CORP (US) | 2007-10-17 | — | — | CN | claimed |