Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.89 |
| ▸ | S1PR3 | Q99500 | 18/20 | 0.89 |
| ▸ | S1PR4 | O95977 | 9/20 | 0.89 |
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27700973 | 1.00 | S1PR1 (0.89) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4981577 | 0.94 | S1PR1 (1.00) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4981567 | 0.94 | S1PR1 (1.00) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL28769408 | 0.83 | S1PR4 (0.62) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL14263263 | 0.82 | S1PR1 (0.89) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4982723 | 0.81 | S1PR1 (1.00) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4610985 | 0.81 | S1PR1 (1.00) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4761196 | 0.81 | S1PR1 (1.00) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4986303 | 0.81 | S1PR1 (1.00) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL14263216 | 0.79 | S1PR1 (0.75) | S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101018761-A | Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity | PRAECIS PHARM INC (US) | 2007-08-15 | — | — | CN | disclosed |