Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701160 | 1.00 | NR1H2 (0.35) | NR1H2NR1H3PTPN1TSHRPREP | |
| SCHEMBL29860555 | 0.81 | NR1H2 (0.43) | NR1H2NR1H3PTPN1PREPSMN1; SMN2 | |
| SCHEMBL17068138 | 0.81 | NR1H2 (0.43) | NR1H2NR1H3PTPN1PREPSMN1; SMN2 | |
| SCHEMBL201569 | 0.81 | NR1H2 (0.37) | NR1H2NR1H3PTPN1SMN1; SMN2HSD17B10 | |
| SCHEMBL201146 | 0.81 | NR1H2 (0.37) | NR1H2NR1H3PTPN1SMN1; SMN2HSD17B10 | |
| SCHEMBL201144 | 0.81 | NR1H2 (0.37) | NR1H2NR1H3PTPN1SMN1; SMN2HSD17B10 | |
| SCHEMBL116263 | 0.79 | CHRM2 (0.41) | NR1H2NR1H3PTPN1PREPSMN1; SMN2 | |
| SCHEMBL21137023 | 0.79 | CHRM2 (0.41) | NR1H2NR1H3PTPN1PREPSMN1; SMN2 | |
| SCHEMBL30181039 | 0.79 | CHRM2 (0.41) | NR1H2NR1H3PTPN1PREPSMN1; SMN2 | |
| SCHEMBL883033 | 0.79 | CHRM2 (0.41) | NR1H2NR1H3PTPN1PREPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101035776-A | Enantiomerically pure heterocyclic compounds for the preparation of peptides potentially useful as medicaments | SOLVAY (BE) | 2007-09-12 | — | — | CN | disclosed |