SCHEMBL27701577

SCHEMBL27701577

CCCCCOC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCD O00767 15/20 0.72
DCTPP1 Q9H773 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1376609 0.89 SCD (0.60) SCDDCTPP1
SCHEMBL27722157 0.89 SCD (0.60) SCDDCTPP1
SCHEMBL27701504 0.85 SCD (0.61) SCDDCTPP1
SCHEMBL937193 0.85 SCD (0.71) SCDDCTPP1
SCHEMBL1376810 0.84 SCD (1.00) SCDDCTPP1
SCHEMBL1381079 0.83 SCD (1.00) SCDDCTPP1
SCHEMBL1380561 0.83 SCD (1.00) SCDDCTPP1
SCHEMBL27654402 0.83 SCD (0.71) SCDDCTPP1
SCHEMBL938162 0.82 SCD (0.62) SCDDCTPP1
SCHEMBL27633597 0.82 SCD (0.69) SCDDCTPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101203244-A Compositions of rennin inhibitor and insulin secernent or insulin sensitizer NOVARTIS AG (CH) 2008-06-18 CN claimed
CN-101163504-A Combination therapy XENON PHARMACEUTICALS INC (CA) 2008-04-16 CN claimed
CN-101203244-A Compositions of rennin inhibitor and insulin secernent or insulin sensitizer NOVARTIS AG (CH) 2008-06-18 CN disclosed
CN-101163504-A Combination therapy XENON PHARMACEUTICALS INC (CA) 2008-04-16 CN disclosed