Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515596 | 0.86 | MEN1 (0.63) | MEN1KMT2AATMKDM4EMAPT | |
| SCHEMBL3857654 | 0.82 | MEN1 (0.88) | MEN1KMT2AATMKDM4EMAPT | |
| SCHEMBL12762818 | 0.81 | MEN1 (0.59) | MEN1KMT2AATMKDM4EMAPT | |
| SCHEMBL28121389 | 0.80 | MEN1 (0.64) | MEN1KMT2AATMKDM4EMAPT | |
| SCHEMBL3862082 | 0.79 | MEN1 (0.78) | MEN1KMT2AATMKDM4EMAPT | |
| SCHEMBL28753703 | 0.78 | MEN1 (0.59) | MEN1KMT2AATMKDM4EMAPT | |
| SCHEMBL28121377 | 0.76 | MEN1 (0.59) | MEN1KMT2AATMKDM4EMAPT | |
| SCHEMBL28846477 | 0.76 | MEN1 (0.61) | MEN1KMT2AATMKDM4EMAPT | |
| SCHEMBL30706300 | 0.76 | MEN1 (0.69) | MEN1KMT2AATMKDM4EMAPT | |
| SCHEMBL3868410 | 0.76 | MEN1 (0.69) | MEN1KMT2AATMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1998770-B1 | USE OF CANTHIN-6-ONE AND ITS ANALOGUES IN THE TREATMENT OF PATHOLOGIES LINKED TO MYCOBACTERIA | INST RECH DEVELOPPEMENT IRD (FR) | 2010-04-21 | — | — | EP | disclosed |
| EP-1998770-A1 | USE OF CANTFFLN-6-ONE AND ITS ANALOGUES IN THE TREATMENT OF PATHOLOGIES LINKED TO MYCOBACTERIA | Institut de Recherche pour le Développement (FR) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007110500-A1 | USE OF CANTHIN-6-ONE AND ITS ANALOGUES IN THE TREATMENT OF PATHOLOGIES LINKED TO MYCOBACTERIA | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2007-10-04 | — | — | WO | disclosed |