Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701661 | 0.85 | HDAC1 (0.33) | HDAC1 | |
| SCHEMBL27722207 | 0.85 | CHRNA1 (0.31) | HDAC1 | |
| SCHEMBL27701753 | 0.84 | CHRM1 (0.33) | HDAC1 | |
| SCHEMBL27701650 | 0.75 | GAA (0.32) | GAAHDAC1 | |
| SCHEMBL27722225 | 0.68 | HDAC1 (0.34) | HDAC1 | |
| SCHEMBL27722260 | 0.65 | HDAC1 (0.36) | GAAHDAC1 | |
| SCHEMBL27722199 | 0.64 | KDM4E (0.39) | GAAHDAC1 | |
| SCHEMBL27722263 | 0.64 | HDAC1 (0.35) | HDAC1 | |
| SCHEMBL27722344 | 0.63 | NR1H4 (0.30) | — | |
| SCHEMBL27701721 | 0.63 | GRIN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |