SCHEMBL27701784

SCHEMBL27701784

C1=Cc2ccccc2CC1.[NaH]

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.39
MAOB P27338 2/20 0.38
TSHR P16473 1/20 0.36
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
KDM1A O60341 1/20 0.33
HTR2C P28335 1/20 0.32
CYP11B1 P15538 2/20 0.31
CYP11B2 P19099 2/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
CYP19A1 P11511 1/20 0.31
NISCH Q9Y2I1 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160705 0.98 PARP1 (0.40) PARP1MAOBTSHRCA1CA2
SCHEMBL29385098 0.98 PARP1 (0.40) PARP1MAOBTSHRCA1CA2
Methane SCHEMBL27705727 0.95 PARP1 (0.39) PARP1MAOBTSHRCA1CA2
Water SCHEMBL27782064 0.95 PARP1 (0.39) PARP1MAOBTSHRCA1CA2
SCHEMBL9420914 0.95 PARP1 (0.39) PARP1MAOBTSHRCA1CA2
Iodide SCHEMBL28897108 0.95 PARP1 (0.39) PARP1MAOBTSHRCA1CA2
Lithium SCHEMBL9420915 0.95 PARP1 (0.39) PARP1MAOBTSHRCA1CA2
SCHEMBL15638199 0.91 PARP1 (0.36) PARP1MAOBTSHRCA1CA2
Naphthalene SCHEMBL8629492 0.91 PARP1 (0.36) PARP1MAOBTSHRCA1CA2
Methyl Alcohol SCHEMBL28176130 0.91 MAOB (0.39) PARP1MAOBTSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101163782-A Lubricant composition SUN CORP CO LTD (JP) 2008-04-16 CN disclosed