SCHEMBL27701979

SCHEMBL27701979

N#Cc1ccccc1O.[KH]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.48
TSHR P16473 3/20 0.48
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 3/20 0.45
MAPT P10636 2/20 0.45
CA2 P00918 2/20 0.45
CYP3A4 P08684 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
NPC1 O15118 1/20 0.45
CA12 O43570 1/20 0.45
GMNN O75496 1/20 0.45
EGFR P00533 1/20 0.45
LMNA P02545 1/20 0.45
FYN P06241 1/20 0.45
POLB P06746 1/20 0.45
CA3 P07451 1/20 0.45
MMP9 P14780 1/20 0.45
ALOX15 P16050 1/20 0.45
NFKB1 P19838 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5756 0.97
SCHEMBL29392995 0.97
SCHEMBL27875336 0.97 TSHR (0.50) ESR2TSHRKDM4EALDH1A1MAPT
Hydrochloric Acid SCHEMBL29026049 0.95 ESR2 (0.48) ESR2TSHRKDM4EALDH1A1MAPT
SCHEMBL31655518 0.95 ESR2 (0.48) ESR2TSHRKDM4EALDH1A1MAPT
Ammonia Solution, Strong SCHEMBL5912983 0.95 ESR2 (0.48) ESR2TSHRKDM4EALDH1A1MAPT
Ammonia Solution, Strong SCHEMBL5912996 0.95 ESR2 (0.48) ESR2TSHRKDM4EALDH1A1MAPT
SCHEMBL31655519 0.95 ESR2 (0.48) ESR2TSHRKDM4EALDH1A1MAPT
SCHEMBL31366240 0.95 ESR2 (0.48) ESR2TSHRKDM4EALDH1A1MAPT
SCHEMBL27495804 0.95 ESR2 (0.48) ESR2TSHRKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685377-B Preparation method of azoxystrobin compound 北京颖泰嘉和生物科技股份有限公司 2024-05-31 CN claimed
CN-114685377-A Preparation method of azoxystrobin compound 北京颖泰嘉和生物科技股份有限公司 2022-07-01 CN claimed
CN-109721548-B Preparation method of azoxystrobin 南通泰禾化工股份有限公司 2020-11-13 CN claimed
CN-101163682-B Process for preparing azoxystrobin using DABCO as catalyst and novel intermediates used in the process SYNGENTA LTD 2012-09-05 CN claimed
CN-101522639-A Preparation of azoxystrobin SYNGENTA LTD (GB) 2009-09-02 CN claimed
CN-101163682-A Process for preparing azoxystrobin using DABCO as catalyst and novel intermediates used in the process SYNGENTA LTD (GB) 2008-04-16 CN claimed
CN-114685377-B Preparation method of azoxystrobin compound 北京颖泰嘉和生物科技股份有限公司 2024-05-31 CN disclosed
CN-114685377-A Preparation method of azoxystrobin compound 北京颖泰嘉和生物科技股份有限公司 2022-07-01 CN disclosed
CN-109721548-B Preparation method of azoxystrobin 南通泰禾化工股份有限公司 2020-11-13 CN disclosed
CN-104974097-B A kind of synthetic method of Fluoxastrobin 重庆紫光化工股份有限公司 2018-04-17 CN disclosed
CN-105246878-B The method for preparing 4,6 pairs of (aryloxy group) pyrimidine derivatives 切米诺瓦有限公司 2017-12-15 CN disclosed
CN-104230819-B Method for synthesizing azoxystrobin 重庆紫光国际化工有限责任公司 2017-05-03 CN disclosed
CN-104230822-B The synthetic method of Fluoxastrobin 重庆紫光国际化工有限责任公司 2017-03-08 CN disclosed
CN-102126955-B Process for preparing azoxystrobin using DABCO as catalyst and novel intermediates used in the process SYNGENTA LTD 2012-12-12 CN disclosed
CN-101163682-B Process for preparing azoxystrobin using DABCO as catalyst and novel intermediates used in the process SYNGENTA LTD 2012-09-05 CN disclosed
CN-102276538-A Method for preparing azoxystrobin and key intermediate thereof 2011-12-14 CN disclosed
CN-102126955-A Process for preparing azoxystrobin using DABCO as catalyst and novel intermediates used in the process SYNGENTA LTD 2011-07-20 CN disclosed
CN-101522642-A Process for preparing 6-phen0xypyrimidin-4-ol derivatives in the presence of a quinuclidine or a n-methyl pyrrolidine derivative SYNGENTA LTD (GB) 2009-09-02 CN disclosed
CN-101522639-A Preparation of azoxystrobin SYNGENTA LTD (GB) 2009-09-02 CN disclosed
CN-101163682-A Process for preparing azoxystrobin using DABCO as catalyst and novel intermediates used in the process SYNGENTA LTD (GB) 2008-04-16 CN disclosed