⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10503416 | 1.00 | TSHR (0.50) | — | |
| SCHEMBL10502961 | 1.00 | TSHR (0.50) | — | |
| SCHEMBL10502952 | 1.00 | TSHR (0.50) | — | |
| SCHEMBL10503065 | 1.00 | TSHR (0.50) | — | |
| SCHEMBL10502676 | 1.00 | TSHR (0.50) | — | |
| SCHEMBL103685 | 1.00 | TSHR (0.50) | — | |
| SCHEMBL4619363 | 1.00 | TSHR (0.50) | — | |
| SCHEMBL104136 | 1.00 | TSHR (0.50) | — | |
| SCHEMBL10503195 | 1.00 | TSHR (0.50) | — | |
| SCHEMBL10505846 | 1.00 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242076-A | Thiophene-based compounds and their use as BCKDK inhibitors | 拉米诺生物公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-116964122-A | Polyurea copolymers | 巴斯夫欧洲公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-112851755-B | Linear lipopeptide compound and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-09-01 | — | — | CN | disclosed |
| CN-116121294-A | Increasing vegetable oil content by altering negative regulatory factors of acetyl-COA carboxylase | 密苏里大学管理者 | 2023-05-16 | — | — | CN | disclosed |
| CN-115003741-A | Cyclohexanol end-capping compounds and their use as plasticizers | 巴斯夫欧洲公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-109385485-B | DNA bar code, primer, kit, method and application | 勐海茶业有限责任公司 | 2021-08-13 | — | — | CN | disclosed |
| US-10927220-B2 | Silazane-siloxane random copolymers, their production and use | AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) | 2021-02-23 | — | — | US | disclosed |
| EP-2478981-B1 | SILVER-(CONJUGATED COMPOUND) COMPLEX | SUMITOMO CHEMICAL CO (JP) | 2020-12-23 | — | — | EP | disclosed |
| US-20200255599-A1 | SILAZANE-SILOXANE RANDOM COPOLYMERS, THEIR PRODUCTION AND USE | AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) | 2020-08-13 | — | — | US | disclosed |
| CN-111499933-A | Low-heat-generation puncture-resistant engineering radial tire base rubber composition and preparation method thereof | 泰凯英(青岛)专用轮胎技术研究开发有限公司 | 2020-08-07 | — | — | CN | disclosed |
| US-7294369-B2 | Polymerisable cinnamates with lateral substitution | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-11-13 | — | — | US | disclosed |
| EP-1845090-A1 | AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |
| EP-1524308-B1 | Polymerisable Cinnamates with lateral substitution | MERCK PATENT GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-20050227021-A1 | Polymerisable cinnamates with lateral substitution | MERCK PATENT GMBH (DE) | 2005-10-13 | — | — | US | disclosed |
| EP-1524308-A1 | Polymerisable Cinnamates with lateral substitution | MERCK PATENT GmbH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-4806675-A | CATALYTIC ESTERIFICATION WITH HYDROXYALKANOIC AND THIOALKANOIC ACIDS; HEAT AND OXIDATION RESISTANCE | MALLINCKRODT, INC. (US) | 1989-02-21 | — | — | US | disclosed |
| US-4794138-A | STABILIZERS OF ORGANIC MATERIAL NORMALLY SUSCEPTIBLE TO OXIDATIVE AND/OR THERMAL DETERIORATION | MALLINCKRODT, INC. (US) | 1988-12-27 | — | — | US | disclosed |
| US-4772741-A | STABILIZERS FOR POLYMERS | MILLINCKRODT, INC. (US) | 1988-09-20 | — | — | US | disclosed |
| US-4734519-A | STABILIZERS | MALLINCKRODT, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0250087-A1 | Pentaerythritol co-esters | MALLINCKRODT, INC. (US) | 1987-12-23 | — | — | EP | disclosed |