Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.48 |
| ▸ | GCGR | P47871 | 5/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26116625 | 0.80 | EGLN1 (0.55) | EGLN1GCGRHDAC6 | |
| SCHEMBL27702865 | 0.78 | EGLN1 (0.45) | EGLN1HDAC6NPC1LMNATP53 | |
| SCHEMBL967008 | 0.77 | EGLN1 (0.56) | EGLN1 | |
| SCHEMBL967496 | 0.75 | EGLN1 (0.56) | EGLN1 | |
| SCHEMBL71292 | 0.71 | HDAC6 (0.71) | HDAC6NPC1LMNATP53HTT | |
| SCHEMBL1219368 | 0.70 | CHRNA7 (0.48) | EGLN1 | |
| SCHEMBL27957411 | 0.68 | EGLN1 (0.66) | EGLN1GCGRHIF1A | |
| SCHEMBL30571780 | 0.67 | KMT2A (0.47) | LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL26572849 | 0.67 | KMT2A (0.47) | LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL71738 | 0.66 | EGLN1 (0.51) | EGLN1HDAC6NPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101166745-A | Thienopyridine compounds and methods of use thereof | FIBROGEN INC (US) | 2008-04-23 | — | — | CN | claimed |
| CN-101166745-A | Thienopyridine compounds and methods of use thereof | FIBROGEN INC (US) | 2008-04-23 | — | — | CN | disclosed |