Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27725306 | 0.89 | MAOB (0.74) | MAOBMAOA | |
| SCHEMBL4203723 | 0.81 | CA12 (0.71) | MAOBMAOANPC1CASP3RAB9A | |
| SCHEMBL4211377 | 0.79 | MAOB (0.68) | MAOBMAOANPC1CASP3RAB9A | |
| SCHEMBL4209951 | 0.79 | MAOB (0.66) | MAOBMAOANPC1CASP3RAB9A | |
| SCHEMBL29116822 | 0.77 | MAOB (0.74) | MAOBMAOANPC1CASP3RAB9A | |
| SCHEMBL20871955 | 0.77 | MCL1 (0.71) | MAOBCA12CA9 | |
| SCHEMBL17931588 | 0.76 | MAOB (0.74) | MAOBMAOANPC1CASP3RAB9A | |
| SCHEMBL29382160 | 0.76 | MAOB (1.00) | MAOBMAOANPC1CASP3RAB9A | |
| SCHEMBL107774 | 0.76 | MAOB (1.00) | MAOBMAOANPC1CASP3RAB9A | |
| SCHEMBL7549311 | 0.76 | MAOB (0.72) | MAOBMAOANPC1CASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101137638-A | Substituted aminoalkyl-and amidoalkyl-benzopyran derivatives | NEWRON PHARM SPA (IT) | 2008-03-05 | — | — | CN | disclosed |