Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE11A | Q9HCR9 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE6C | P51160 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916952 | 0.85 | PDE11A (0.42) | PDE11AMAPTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL3026830 | 0.77 | PDE11A (0.43) | PDE11AMAPTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL2918449 | 0.76 | HTR2C (0.47) | MAPTALDH1A1KMT2AHSD17B10MEN1 | |
| SCHEMBL3948726 | 0.75 | CETP (0.45) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL2922786 | 0.75 | HTT (0.36) | PDE11AMAPTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL2920928 | 0.75 | ESR1 (0.36) | PDE11AMAPTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL2911656 | 0.75 | MEN1 (0.34) | PDE11AMAPTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL13212462 | 0.74 | PDE11A (0.37) | PDE11AMAPTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL2923250 | 0.73 | KMT2A (0.41) | PDE11AMAPTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL3027474 | 0.73 | CHRNA10 (0.37) | PDE11AALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163706-A | Dihydrothienopyrimidines for the treatment of inflammatory diseases | BOEHRINGER INGELHEIM INT (DE) | 2008-04-16 | — | — | CN | disclosed |