Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706920 | 0.94 | MAPT (0.51) | MAPTCACNA1BAPBA1APPHCAR2 | |
| SCHEMBL28068994 | 0.88 | TSHR (0.43) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL36375 | 0.87 | MAPT (0.69) | MAPTCACNA1BAPBA1APPHCAR2 | |
| SCHEMBL36140 | 0.87 | MAPT (0.69) | MAPTCACNA1BAPBA1APPHCAR2 | |
| SCHEMBL36139 | 0.87 | MAPT (0.69) | MAPTCACNA1BAPBA1APPHCAR2 | |
| SCHEMBL6885967 | 0.87 | MAPT (0.69) | MAPTCACNA1BAPBA1APPHCAR2 | |
| SCHEMBL7809907 | 0.84 | MAPT (0.67) | MAPTCACNA1BAPBA1APPHCAR2 | |
| Ethylene SCHEMBL28241615 | 0.84 | MAPT (0.67) | MAPTCACNA1BAPBA1APPHCAR2 | |
| SCHEMBL7809914 | 0.84 | MAPT (0.67) | MAPTCACNA1BAPBA1APPHCAR2 | |
| SCHEMBL29973550 | 0.84 | MAPT (0.53) | MAPTCACNA1BAPBA1APPHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163523-B | Tooth whitening compositions containing cross-linked polymer-peroxide | COLGATE PALMOLIVE CO | 2013-06-19 | — | — | CN | disclosed |
| CN-101163523-A | Tooth whitening compositions containing cross-linked polymer-peroxide | COLGATE PALMOLIVE CO (US) | 2008-04-16 | — | — | CN | disclosed |