Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.70 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.70 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924364 | 0.97 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2788402 | 0.94 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2771440 | 0.92 | PDE4B (0.59) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2773801 | 0.92 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2785394 | 0.90 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL7925362 | 0.90 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2787887 | 0.89 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2787042 | 0.89 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL7924367 | 0.89 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2789292 | 0.87 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |