SCHEMBL27706231

SCHEMBL27706231

Nc1nc(/C(=N/O)C(=O)S)ns1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27813307 1.00
SCHEMBL3078362 0.85 GAA (0.37)
SCHEMBL8573096 0.84 GAA (0.32)
SCHEMBL9016599 0.84 GAA (0.32)
SCHEMBL9876380 0.84 GAA (0.32)
SCHEMBL16091103 0.82
SCHEMBL3078360 0.82
SCHEMBL27813231 0.80
SCHEMBL27698354 0.80
SCHEMBL2456129 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102050831-B Cephalosporin derivative KBP BIOSCIENCES CO LTD 2014-02-26 CN disclosed
CN-102030766-B Cephalosporin antibiotics containing dihydropyrroloheterocycles SHANDONG XUANZHU MEDICAL TECHNOLOGY CO LTD 2012-08-08 CN disclosed
CN-101798315-B Cephalosporin derivative containing aza-cyclopropane nitrogen heterocyclic ring KBP BIOSCIENCES CO LTD 2012-07-04 CN disclosed
CN-101899059-B Pyrrolidine-containing tricyclic cephalosporin derivatives XUANZHU PHARMA CO.,LTD. (CN) 2012-02-15 CN disclosed
CN-101759710-B Cephalosporin derivatives containing substituted nitrogen heterocycles SHANDONG XUANZHU PHARM TECH CO 2011-10-05 CN disclosed
CN-102070655-A Imidazole ring-containing cephalosporin derivative SHANDONG XUANZHU MEDICAL TECHNOLOGY CO LTD 2011-05-25 CN disclosed
CN-102070656-A Substituted imidazole ring-containing cephalosporin derivatives SHANDONG XUANZHU MEDICAL TECHNOLOGY CO LTD 2011-05-25 CN disclosed
CN-102040615-A Cephalosporin antibiotics containing dihydropyrrolocycloalkyl SHANDONG XUANZHU MEDICAL SCI TECH CO LTD 2011-05-04 CN disclosed
CN-102030766-A Cephalosporin antibiotics containing dihydropyrroloheterocycles SHANDONG XUANZHU MEDICAL TECHNOLOGY CO LTD 2011-04-27 CN disclosed
CN-101899059-A Pyrrolidine-containing tricyclic cephalosporin derivatives KBP BIOSCIENCES CO LTD 2010-12-01 CN disclosed
CN-101759710-A Cephalosporin derivatives containing substituted nitrogen heterocycles SHANDONG XUANZHU PHARM TECH CO 2010-06-30 CN disclosed
CN-101190922-B Cephalosporin derivative SHANDONG XUANZHU MEDICINE TECHNOLOGY CO LTD 2010-06-02 CN disclosed
CN-101712689-A Azepine condensed ring substituted cephalosporin derivative SHANDONG XUANZHU PHARM TECH CO 2010-05-26 CN disclosed
CN-101230070-A Novel anti-infection cephalosporin compounds ZHENHUA HUANG (CN) 2008-07-30 CN disclosed
CN-101190922-A Cephalosporin derivative ZHENHUA HUANG (CN) 2008-06-04 CN disclosed