Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 9/20 | 0.64 |
| ▸ | SRC | P12931 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | YES1 | P07947 | 1/20 | 0.52 |
| ▸ | HCK | P08631 | 1/20 | 0.52 |
| ▸ | PAK3 | O75914 | 2/20 | 0.49 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.49 |
| ▸ | PAK2 | Q13177 | 2/20 | 0.49 |
| ▸ | IGF1R | P08069 | 2/20 | 0.49 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641518 | 0.83 | NTRK1 (0.67) | NTRK1IGF1RNEK1 | |
| SCHEMBL27708659 | 0.83 | NTRK1 (0.56) | NTRK1IGF1R | |
| SCHEMBL22535735 | 0.78 | NTRK1 (0.72) | NTRK1IGF1R | |
| SCHEMBL4151801 | 0.77 | NTRK1 (0.59) | NTRK1IGF1R | |
| SCHEMBL4065423 | 0.76 | NTRK1 (0.80) | NTRK1IGF1R | |
| SCHEMBL23216996 | 0.76 | NTRK1 (0.83) | NTRK1IGF1R | |
| SCHEMBL22535428 | 0.76 | NTRK1 (0.64) | NTRK1IGF1R | |
| SCHEMBL3342109 | 0.76 | NTRK1 (0.83) | NTRK1IGF1R | |
| SCHEMBL22535313 | 0.75 | NTRK1 (0.63) | NTRK1IGF1R | |
| SCHEMBL22535599 | 0.75 | NTRK1 (0.66) | NTRK1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208093-A | Use of pyrazolyl-pyrimidine derivatives in the treatment of pain | ASTRAZENECA AB CLAESSON ALF (SE) | 2008-06-25 | — | — | CN | disclosed |