Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28391580 | 0.84 | TSHR (0.48) | TSHRPPARGPPARAKMT2AMTNR1A | |
| SCHEMBL10938219 | 0.84 | TSHR (0.58) | TSHRPPARGPPARAKMT2AALDH1A1 | |
| SCHEMBL9417319 | 0.83 | KMT2A (0.47) | TSHRPPARGPPARAKMT2AMTNR1A | |
| SCHEMBL17724580 | 0.83 | TSHR (0.47) | TSHRPPARGPPARAKMT2AMTNR1A | |
| SCHEMBL10519863 | 0.83 | TSHR (0.47) | TSHRPPARGPPARAKMT2AMTNR1A | |
| SCHEMBL7329105 | 0.82 | TSHR (0.44) | TSHRPPARGPPARAKMT2AMTNR1A | |
| SCHEMBL27688923 | 0.82 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL29163290 | 0.81 | PPARG (0.65) | PPARGPPARAPTPN1 | |
| SCHEMBL7335069 | 0.81 | PPARG (0.55) | TSHRPPARGPPARAKMT2AMTNR1A | |
| SCHEMBL9417307 | 0.81 | TSHR (0.46) | TSHRPPARGPPARAKMT2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115731-A | Oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-01-30 | — | — | CN | claimed |
| CN-101115731-A | Oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-01-30 | — | — | CN | disclosed |