Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.63 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5433876 | 0.94 | CYP1A2 (0.58) | TRPV1TNIKNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5433870 | 0.94 | CYP1A2 (0.58) | TRPV1TNIKNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1949534 | 0.87 | HTT (0.70) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL1949533 | 0.87 | HTT (0.70) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL5427446 | 0.85 | HTT (0.68) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| Guanidine SCHEMBL27709634 | 0.85 | HTT (0.68) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL5427447 | 0.85 | HTT (0.68) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL5436010 | 0.84 | TRPV1 (0.52) | TRPV1TNIKHTTNPC1RAB9A | |
| SCHEMBL5436012 | 0.84 | TRPV1 (0.52) | TRPV1TNIKHTTNPC1RAB9A | |
| SCHEMBL5431007 | 0.81 | HDAC2 (0.66) | HTTPOLBKMT2AHDAC8HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101111475-A | Antiviral compounds and methods | BIOTRON LTD (AU) | 2008-01-23 | — | — | CN | disclosed |