Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 10/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767897 | 0.80 | SMO (0.37) | LMNAHTTKMT2A | |
| SCHEMBL3759702 | 0.79 | MAPT (0.53) | KDM4ECYP2C19HSD17B10NPSR1LMNA | |
| SCHEMBL3765914 | 0.78 | HSD17B10 (0.37) | KDM4EHSD17B10HPGDLMNAMAPT | |
| SCHEMBL725443 | 0.77 | KDM4E (0.71) | KDM4ECYP2C19HSD17B10USP2HPGD | |
| SCHEMBL3770598 | 0.74 | HRH1 (0.39) | KDM4ECYP2C19HSD17B10USP2HPGD | |
| SCHEMBL12716919 | 0.71 | KDM4E (0.68) | KDM4ECYP2C19HSD17B10USP2HPGD | |
| SCHEMBL10055200 | 0.70 | KDM4E (0.61) | KDM4ECYP2C19HSD17B10USP2HPGD | |
| SCHEMBL12644983 | 0.70 | KDM4E (0.71) | KDM4ECYP2C19HSD17B10USP2HPGD | |
| SCHEMBL725986 | 0.70 | KDM4E (0.61) | KDM4ECYP2C19HSD17B10USP2HPGD | |
| SCHEMBL2384642 | 0.70 | NEK2 (0.48) | KDM4ECYP2C19HSD17B10USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101103007-A | Amide compound | TAKEDA PHARMACEUTICAL (JP) | 2008-01-09 | — | — | CN | disclosed |