Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502521 | 0.96 | TYMP (0.40) | TYMPALDH1A1CYP3A4ELANEACMSD | |
| SCHEMBL9278169 | 0.86 | TYMP (0.42) | TYMPALDH1A1CYP3A4ELANEACMSD | |
| Ethylene SCHEMBL28695708 | 0.81 | TYMP (0.38) | TYMPALDH1A1CYP3A4ELANEACMSD | |
| SCHEMBL18244172 | 0.81 | TYMP (0.41) | TYMPALDH1A1CYP3A4ELANEACMSD | |
| SCHEMBL2105114 | 0.81 | TYMP (0.41) | TYMPALDH1A1CYP3A4ELANEACMSD | |
| SCHEMBL11201526 | 0.81 | TYMP (0.41) | TYMPALDH1A1CYP3A4ELANEACMSD | |
| SCHEMBL18244171 | 0.81 | TYMP (0.41) | TYMPALDH1A1CYP3A4ELANEACMSD | |
| SCHEMBL21057468 | 0.81 | TYMP (0.41) | TYMPALDH1A1CYP3A4ELANEACMSD | |
| SCHEMBL3502363 | 0.81 | TYMP (0.41) | TYMPALDH1A1CYP3A4ELANEACMSD | |
| SCHEMBL3796623 | 0.81 | TYMP (0.41) | TYMPALDH1A1CYP3A4ELANEACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097925-B1 | NOVEL BENZOIC ACID DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NIPPON SODA CO (JP) | 2006-09-13 | — | — | EP | claimed |
| US-6756497-B1 | REACTING SUBSTITUTED BICYCLOHEPTENONE WITH ALKALI METAL ALKOXIDE OR ALKALI METAL OR ALKALINE EARTH METAL HYDROXIDE AND WATER OR METHANOL, ETHANOL, PROPANOL, ISOPROPANOL, BUTANOL OR TERT-BUTANOL IN LISTED ALCOHOLS OR TETRAHYDROFURAN AS SOLVENT | NIPPON SODA CO., LTD. (JP) | 2004-06-29 | — | — | US | claimed |
| EP-1097925-A1 | NOVEL BENZOIC ACID DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NIPPON SODA CO., LTD. (JP) | 2001-05-09 | — | — | EP | claimed |
| EP-0074856-A2 | Resolution of racemic bicycloheptenones | GLAXO GROUP LIMITED (GB) | 1983-03-23 | — | — | EP | claimed |
| CN-117242065-A | Indole derivatives as serotonergic agents for the treatment of diseases associated therewith | 明德赛特制药公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-115974757-A | Silodosin derivatives as serotonergic hallucinogens for the treatment of CNS disorders | 明德赛特制药公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-115427395-A | Silodosin derivatives as serotonergic hallucinogens for the treatment of CNS disorders | 明德赛特制药公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115414480-A | Dianhydrogalactitol in combination with radiation for treatment of non-small cell lung cancer and glioblastoma multiforme | 德玛医药 | 2022-12-02 | — | — | CN | disclosed |
| CN-115397810-A | Silodosin derivatives as serotonergic hallucinogens for the treatment of CNS disorders | 明德赛特制药公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-115380028-A | 3-pyrrolidine-indole derivatives as serotonergic hallucinogens for the treatment of CNS disorders | 明德赛特制药公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-109942595-B | Oxygen-bridged bicyclo- [2.2.1] -heptene compounds containing different functional side chain structures and preparation and application thereof | 武汉大学 | 2020-08-25 | — | — | CN | disclosed |
| CN-107257846-A | With the stabilized laundry detergent composition of amphiphilic rheology modifier with amphiphilic cross-linking agents | 路博润先进材料公司 | 2017-10-17 | — | — | CN | disclosed |
| EP-0160495-A2 | Cyclopentyl ethers and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1985-11-06 | — | — | EP | disclosed |
| EP-0100900-A1 | Novel (3.2.0.) bicycloheptanone oxime ethers with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1984-02-22 | — | — | EP | disclosed |
| EP-0074856-A3 | RESOLUTION OF RACEMIC BICYCLOHEPTENONES | GLAXO GROUP LIMITED (GB) | 1984-02-01 | — | — | EP | disclosed |
| EP-0074856-A3 | RESOLUTION OF RACEMIC BICYCLOHEPTENONES | GLAXO GROUP LIMITED (GB) | 1984-02-01 | — | — | EP | disclosed |
| US-4423068-A | (3.2.0) Bicycloheptanone oxime ethers with therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1983-12-27 | — | — | US | disclosed |
| EP-0074856-A2 | Resolution of racemic bicycloheptenones | GLAXO GROUP LIMITED (GB) | 1983-03-23 | — | — | EP | disclosed |
| EP-0074856-A2 | Resolution of racemic bicycloheptenones | GLAXO GROUP LIMITED (GB) | 1983-03-23 | — | — | EP | disclosed |
| EP-0074856-A2 | Resolution of racemic bicycloheptenones | GLAXO GROUP LIMITED (GB) | 1983-03-23 | — | — | EP | disclosed |