Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.93 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28327973 | 0.97 | TSHR (0.88) | TSHRDPP4F2HTR2ATAAR1 | |
| SCHEMBL28353 | 0.97 | — | — | |
| Fluoride SCHEMBL28106560 | 0.93 | TSHR (0.93) | TSHRDPP4F2HTR2ATAAR1 | |
| Water SCHEMBL11889376 | 0.93 | TSHR (0.93) | TSHRDPP4F2HTR2ATAAR1 | |
| SCHEMBL27797843 | 0.93 | TSHR (0.93) | TSHRDPP4F2HTR2ATAAR1 | |
| SCHEMBL30292633 | 0.93 | TSHR (0.93) | TSHRDPP4F2HTR2ATAAR1 | |
| Hydrochloric Acid SCHEMBL28478207 | 0.93 | TSHR (0.93) | TSHRDPP4F2HTR2ATAAR1 | |
| SCHEMBL7032625 | 0.93 | TSHR (0.93) | TSHRDPP4F2HTR2ATAAR1 | |
| Fluoride SCHEMBL28951268 | 0.93 | TSHR (0.93) | TSHRDPP4F2HTR2ATAAR1 | |
| Hydrochloric Acid SCHEMBL27973361 | 0.93 | TSHR (0.93) | TSHRDPP4F2HTR2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101061090-B | Preparation method of alpha, alpha-difluoroamine | HOKKAIDO UNIV NAT UNIVERSITY CORP | 2011-06-15 | — | — | CN | disclosed |
| CN-101061090-A | Preparation method of alpha, alpha-difluoroamine | UNIV HOKKAIDO NAT UNIV CORP (JP) | 2007-10-24 | — | — | CN | disclosed |