Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540678 | 0.89 | HTT (0.40) | NPC1RAB9ACA12CA9APOBEC3A | |
| SCHEMBL4973158 | 0.75 | CYP19A1 (0.45) | ALDH1A1 | |
| SCHEMBL27712800 | 0.73 | ELANE (0.37) | ALDH1A1LMNA | |
| SCHEMBL16094019 | 0.72 | — | — | |
| SCHEMBL11265868 | 0.70 | ELANE (0.34) | — | |
| SCHEMBL2200339 | 0.70 | NPSR1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL9690903 | 0.70 | CHRM2 (0.51) | TSPOCRHBPCRHR2NPC1RAB9A | |
| SCHEMBL18429032 | 0.69 | CHRM2 (0.50) | TSPOCRHBPCRHR2NPC1RAB9A | |
| SCHEMBL8187887 | 0.68 | KMT2A (0.34) | LMNA | |
| SCHEMBL27359652 | 0.68 | KMT2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101010315-A | Substituted pyrazolyl urea derivatives useful in the treatment of cancer | BAYER PHARMACEUTICALS CORP (US) | 2007-08-01 | — | — | CN | claimed |
| CN-101010315-A | Substituted pyrazolyl urea derivatives useful in the treatment of cancer | BAYER PHARMACEUTICALS CORP (US) | 2007-08-01 | — | — | CN | disclosed |