Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 19/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | HRH1 | P35367 | 5/20 | 0.57 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3582288 | 0.92 | SSTR5 (0.68) | SSTR5KCNH2HRH1SSTR1HTR2B | |
| SCHEMBL27715570 | 0.91 | SSTR5 (0.62) | SSTR5KCNH2HRH1SSTR1HTR2B | |
| SCHEMBL3577720 | 0.88 | SSTR5 (0.70) | SSTR5HRH1HTR2B | |
| SCHEMBL27715573 | 0.83 | SSTR5 (0.78) | SSTR5KCNH2HRH1SSTR1HTR2B | |
| SCHEMBL3571041 | 0.82 | SSTR5 (0.72) | SSTR5KCNH2HRH1SSTR1HTR2B | |
| SCHEMBL3578610 | 0.79 | SSTR5 (0.78) | SSTR5HRH1HTR2B | |
| SCHEMBL3568789 | 0.77 | SSTR5 (0.78) | SSTR5KCNH2HRH1SSTR1HTR2B | |
| SCHEMBL27715355 | 0.77 | SSTR5 (0.75) | SSTR5KCNH2HRH1SSTR1HTR2B | |
| SCHEMBL27695335 | 0.76 | SSTR5 (0.75) | SSTR5KCNH2HRH1SSTR1 | |
| SCHEMBL27715563 | 0.76 | SSTR5 (0.88) | SSTR5KCNH2HRH1SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101137660-B | Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives as antidiabetic compounds | HOFFMANN LA ROCHE | 2011-06-15 | — | — | CN | disclosed |
| CN-101137660-A | Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives as antidiabetic compounds | HOFFMANN LA ROCHE (CH) | 2008-03-05 | — | — | CN | disclosed |