Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27759768 | 0.97 | CYP19A1 (0.44) | CYP19A1KMT2AMEN1HSD17B10GCGR | |
| Formamide SCHEMBL27704471 | 0.89 | CYP19A1 (0.46) | CYP19A1KMT2AMEN1HSD17B10GCGR | |
| Formic Acid SCHEMBL27456543 | 0.86 | KMT2A (0.47) | CYP19A1KMT2AMEN1HSD17B10GCGR | |
| SCHEMBL14690989 | 0.85 | — | — | |
| SCHEMBL6842 | 0.85 | — | — | |
| SCHEMBL4735385 | 0.85 | CYP19A1 (0.57) | CYP19A1KMT2AMEN1GCGRNT5E | |
| Formic Acid SCHEMBL27691334 | 0.84 | KMT2A (0.45) | CYP19A1KMT2AMEN1HSD17B10GCGR | |
| Formaldehyde SCHEMBL27738996 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL25275623 | 0.82 | — | — | |
| SCHEMBL29843433 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101432281-B | 6-0-substituted benzoxazole and benzothiazole compounds and methods of inhibiting CSF-1R signaling | NOVARTIS AG | 2013-08-28 | — | — | CN | disclosed |
| CN-101273009-B | Insecticidal 3-acylaminobenzanilides | BAYER CROPSCIENCE AG | 2012-09-05 | — | — | CN | disclosed |
| CN-101432281-A | 6-O-substituted benzoxazole and benzothiazole compounds and methods for inhibiting CSF-1R signaling | NOVARTIS AG (CH) | 2009-05-13 | — | — | CN | disclosed |
| CN-101273009-A | Insecticidal 3-acylaminobenzanilides | BAYER CROPSCIENCE AG (DE) | 2008-09-24 | — | — | CN | disclosed |